Of late, curcumin has been promoted as a natural pain killer. The body enzyme named COX-2 is primarily responsible for pain and inflammation. According to researchers, curcumin acts upon this enzyme and blocks it action, thereby reducing inflammation and pain. So, it is now used for relieving pain and inflammation associated with conditions, like arthritis, asthma, and colitis. However, there is no conclusive proof for the effectiveness of curcumin in relieving pain.